The Shasta Cascade region of California is located in the northeastern and north-central sections of the state bordering Oregon and Nevada, including far northern parts of the Central Valley and the Sierra Nevada mountain range. The area is centered on Mount Shasta in the California Cascade Range, near the Trinity Alps. Mount Shasta is a dormant volcano; nearby Lassen Peak is recently active.

The civic "capital" of the Shasta Cascade area is Redding; other cities and towns are Alturas, Biggs, Chico, Dunsmuir, Mt. Shasta, Red Bluff Oroville, Weed, Fall River, Burney, and Yreka. Counties included in the Shasta Cascade region include Butte, Lassen, Modoc, Plumas, Shasta, Siskiyou, Tehama and Trinity.

There are seven national forests in the Shasta Cascade region: Klamath National Forest, Lassen National Forest, Mendocino National Forest, Modoc National Forest, Plumas National Forest and Shasta-Trinity National Forest, as well as the Lava Beds National Monument.

The Shasta Cascade is also well-known for its numerous lakes, rivers, and waterfalls, including Shasta Lake, Trinity Lake, Lake Almanor, Eagle Lake, and Lake Siskiyou, the Sacramento River, McCloud River, and Trinity River, as well as Mossbrae Falls, the McCloud River Falls, and Burney Falls.

Numerous parks and recreation opportunities fill the Shasta Cascade including Shasta Lake, Lake Siskiyou, Castle Crags State Park, a new park at Upper Soda Springs, the Trinity Alps, Clair Engle Lake, Castle Lake, Lassen Volcanic National Park, Caribou Wilderness, Thousand Lakes Wilderness, and of course climbing Mount Shasta.

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